Just found out from my sis, who works for a large pharmaceutical company, that seville oranges can have the same (negative) effect on certain medications as grapefruit juice (which we are told to avoid, both pre and post transplant). The info. below has been taken from a website I found on Google:
"For patients on medications that require careful control of blood levels to avoid toxicity, such as amiodarone (Cordarone, and others), carbamazepine (Tegretol, and others), cyclosporine (Sandimmune, and others), sirolimus (Rapamune), and tacrolimus (Prograf), we recommend the avoidance of grapefruits, grapefruit juice, and Seville oranges altogether."
I asked my sis whether this also related to eating orange marmalade, as Seville oranges are used to make this, and she informed me that it can have a potentially disastrous effect on transplant patients. Thought I would pass this on as soon as I found this out - another thing to add to our list of do's and don'ts.
Ruth